lupe denotes sorrow or distress arising from loss, suffering, painful news, or an unwelcome circumstance.

The attested noun denotes sorrow or distress in varied painful circumstances: hearts filled after difficult words, weeping and lamenting, unjust suffering, concern over loss, and pain that may give way to joy or a later good outcome.

1. Sorrow amid suffering, loss, or painful circumstances · dominant

   The noun names distress that fills the heart in John 16:6, accompanies weeping and lamenting before turning to joy in John 16:20, and is experienced by a woman at childbirth in John 16:21. It also occurs for the disciples' condition in Luke 22:45, sorrow added to sorrow in Philippians 2:27, and hardships endured unjustly in 1 Peter 2:19.

   John 16:6John 16:20John 16:21Luke 22:45Philippians 2:271 Peter 2:19

In the Anselm Project Bible: The APB commonly presents the noun with "grief" or "sorrow," including sorrow in the heart and sorrow upon sorrow. Its wording confirms the verses' overall portrayal of distress rather than fixing a separate English equivalent in every clause.