sha.qats describes rejecting forbidden things and, in related warnings, becoming detestable through defilement.

The clearest use is commanded rejection of an abominable object or prohibited creatures. In two warnings, the verb is used in clauses about making oneself detestable through contact with what is unclean; the supplied translation does not isolate its contribution in Psalm 22:25.

1. Rejecting forbidden objects or creatures · dominant

   In Deuteronomy 7:26, the infinitive-absolute form occurs in the command not to bring an abomination into the house; the APB renders the clause “you shall utterly detest it and abhor it.” In Leviticus 11:11 and Leviticus 11:13, imperfect forms occur in instructions concerning creatures that are not to be eaten, with the APB rendering “you shall detest their carcass” and “These you shall detest among the birds.” Psalm 22:25 has a perfect form in a verse of praise and vows, but the supplied APB text does not identify a corresponding English expression, so it does not establish a further nuance.

   Deuteronomy 7:26Leviticus 11:11Leviticus 11:13Psalm 22:25
2. Making oneself detestable through defilement · common

   In Leviticus 11:43, a Piel jussive occurs in the warning not to make yourselves detestable with swarming creatures or become unclean by them. Leviticus 20:25 similarly places a Piel imperfect in the command to distinguish clean from unclean animals and not make yourselves detestable with them.

   Leviticus 11:43Leviticus 20:25

In the Anselm Project Bible: The APB renders the legal clauses with “detest,” “utterly detest,” and “make yourselves detestable.” Its wording cannot isolate the term’s contribution in Psalm 22:25.