Hupomeno describes continuing through suffering, hostility, testing, or affliction, and in two narratives remaining in a place.

The prevailing use describes continuing through hostility, suffering, affliction, discipline, or testing: those who do so are spoken of as enduring to the end or through a trial. In two narrative settings, the verb instead marks people remaining where they are.

1. Continuing through hardship or opposition · dominant

   In Matthew 10:22 and Mark 13:13, the aorist participle identifies the person who continues to the end amid being hated; the APB renders the clause "the one who endures to the end will be saved." In Hebrews 12:2, the aorist indicative concerns enduring the cross and its shame, while Hebrews 10:32 recalls continuing through "a hard struggle with sufferings." Present forms also occur with affliction, discipline, temptation, and love in Romans 12:12, Hebrews 12:7, James 1:12, and 1 Corinthians 13:7.

   Matthew 10:22Mark 13:13Hebrews 10:32Hebrews 12:2James 1:12Romans 12:12
2. Remaining in a location · rare

   In Acts 17:14, the aorist indicative plural refers to Silas and Timothy remaining there after Paul is sent away. In Luke 2:43, the aorist indicative singular refers to Jesus remaining in Jerusalem while his parents return.

   Acts 17:14Luke 2:43

In the Anselm Project Bible: The APB commonly presents the hardship use with "endure" or "endures," including suffering, the cross, temptation, and affliction. In Acts 17:14 and Luke 2:43 it uses "remained"; these are verse-level renderings rather than definitions.