what
ma marks a question about the means of an action or an indefinite matter to be done.
As a function word, ma marks an interrogative question in 1 Kings 22:21 and an indefinite reference to the action required in Ezra 6:8.
Senses in use
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Interrogative and indefinite reference marker · dominant
In 1 Kings 22:21, the interrogative particle occurs in the LORD's response to the spirit's proposal, and the APB renders the question "With what?" In Ezra 6:8, the indefinite pronoun introduces the matter addressed by the decree; the APB renders the clause "concerning what you shall do with those elders of the Jews."
In the Anselm Project Bible: The APB presents the occurrence in 1 Kings 22:21 as "With what?" and in Ezra 6:8 within "what you shall do." These renderings show the clauses rather than a fixed English equivalent.