ya.ash describes giving up expectation or judging a course hopeless, including ceasing to pursue or responding in despair.

The attested uses describe giving up expectation or treating a situation as hopeless: Saul ceases seeking David, a heart turns toward despair over labor, and speakers declare hopelessness while continuing in their chosen course. The supplied rendering for Job 6:26 does not isolate the term’s contribution clearly.

1. Giving up hope or treating a course as hopeless · dominant

   In 1 Samuel 27:1, the Niphal perfect occurs in David’s expectation that Saul will stop seeking him; the APB renders the clause, “Saul will despair of seeking me any longer.” The Niphal participle appears in declarations of hopelessness in Isaiah 57:10, Jeremiah 18:12, and Jeremiah 2:25, while Ecclesiastes 2:20 uses a Piel infinitive construct for turning the heart toward despair over labor; the APB renders these clauses with “It is hopeless” and “to despair.” In Job 6:26, the supplied APB renders the surrounding question about rebuking words as wind, without making this term’s specific English contribution clear.

   1 Samuel 27:1Ecclesiastes 2:20Isaiah 57:10Jeremiah 18:12Jeremiah 2:25Job 6:26

In the Anselm Project Bible: The APB presents the clearer clauses with “despair,” “hopeless,” and Saul’s abandoning his search in 1 Samuel 27:1. Job 6:26 cannot be assigned a specific English rendering from the supplied text.