Holoteles describes an all-encompassing completeness in the prayer for believers’ sanctification.

Its sole attested use describes completeness encompassing the person addressed in a prayer that God sanctify them.

1. Complete sanctification of those addressed · dominant

   In 1 Thessalonians 5:23, the accusative plural masculine form occurs in the prayer that the God of peace sanctify the addressees; the clause then speaks of their whole spirit, soul, and body being kept blameless. The APB renders the prayer, “May the God of peace himself sanctify you completely,”.

   1 Thessalonians 5:23

In the Anselm Project Bible: In 1 Thessalonians 5:23, the APB presents the clause with “sanctify you completely.” That wording indicates the clause’s overall presentation rather than a precise token-by-token rendering.