surely not
medamos is an emphatic refusal spoken in response to the command concerning common or unclean food.
The attested use is an emphatic negative reply: in both occurrences, it introduces a refusal connected with eating anything described as common or unclean.
Senses in use
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Emphatic refusal of the proposed eating · dominant
The adverbial form introduces Peter's negative response to the command: in Acts 10:14 the APB renders the reply "Surely not, Lord," before his statement that he has never eaten anything common or unclean. The same refusal recurs in Acts 11:8, where the APB renders "By no means, Lord," before the statement that nothing common or unclean has entered his mouth.
In the Anselm Project Bible: The APB varies its presentation between "Surely not" in Acts 10:14 and "By no means" in Acts 11:8. These renderings confirm the force of the replies without establishing separate senses.